Borussia Dortmund have won six of their last eight matches in all competitions, with their only defeats in that run coming in the league. They fell to a 2-1 loss at home at the weekend, which is hardly ideal preparation for the welcome of Lazio.
That said, the Serie A side lost 3-1 to Udinese on Sunday, that ending an eight-match unbeaten streak. Away from home they have lost just once this season and won the reverse fixture back in Rome.
Borussia Dortmund have won their two home Champions League matches this season and it wouldn't be a surprise to see the German side make it three from three at Lazio's expense.